The breeding habitat is along freshwater ponds and small lakes, and in forests inhabited by Northern Flickers. They winter in shallow saltwater, or in lakes and rivers. They are cavity nesters, lined with down from the chest of the female. The trees used are mostly poplar, aspen, or fir, and pine tress are used in California, all of which have been excavated by Norther Flickers and Pileated Woodpeckers. Nest sites are reused for several years, expecially if there was a successful clutch hatching the year before. The clutch size is 4 to 17 eggs, that are cream or raw sienna. Buffleheads are mostly monogamous, remaining with the same mate for several years.
Their diet is mostly aquatic invertebrates (insects, crustaceans, molluscs) and some seeds.